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Peroxisome Proliferator-Activated-γ Coactivator-1α–Mediated Mitochondrial Biogenesis Is Important for Hematopoietic Recovery in Response to Stress

Hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) play a vital role in replenishment of blood cells. In addition to growth factors, energy metabolism plays an important role in cellular proliferation. Oxidative phosphorylation that occurs in the mitochondria is the major sour...

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Hlavní autoři: Basu, Sunanda, Broxmeyer, Hal E., Hangoc, Giao
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657284/
https://ncbi.nlm.nih.gov/pubmed/23311338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0466
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