A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway

The calcium, calmodulin-dependent phosphatase calcineurin, regulates growth and gene expression of striated muscles. The activity of calcineurin is modulated by a family of cofactors, referred to as modulatory calcineurin-interacting proteins (MCIPs). In the heart, the MCIP1 gene is activated by cal...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Bush, Erik, Fielitz, Jens, Melvin, Lawrence, Martinez-Arnold, Michael, McKinsey, Timothy A., Plichta, Ryan, Olson, Eric N.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2004
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14976250/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308723101
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!