Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo

The adult myocardium responds to a variety of pathologic stimuli by hypertrophic growth that frequently progresses to heart failure. The calcium/calmodulin-dependent protein phosphatase calcineurin is a potent transducer of hypertrophic stimuli. Calcineurin dephosphorylates members of the nuclear fa...

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Bibliografiske detaljer
Main Authors: Antos, Christopher L., McKinsey, Timothy A., Frey, Norbert, Kutschke, William, McAnally, John, Shelton, John M., Richardson, James A., Hill, Joseph A., Olson, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC117404/
https://ncbi.nlm.nih.gov/pubmed/11782539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231619298
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