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Mitochondrial Respiratory Pathways Inhibition in Rhizopus oryzae Potentiates Activity of Posaconazole and Itraconazole via Apoptosis
The incidence of mucormycosis has increased drastically in immunocompromised patients. Also the array of targets whose inhibition results in Mucorales death is limited. Recently, researchers identified mitochondria as important regulators of detoxification and virulence mechanisms in fungi. In this...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656966/ https://ncbi.nlm.nih.gov/pubmed/23696824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063393 |
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