Hyperthermia Sensitizes Rhizopus oryzae to Posaconazole and Itraconazole Action through Apoptosis

The high mortality rate of mucormycosis with currently available monotherapy has created interest in studying novel strategies for antifungal agents. With the exception of amphotericin B (AMB), the triazoles (posaconazole [PCZ] and itraconazole [ICZ]) are fungistatic in vitro against Rhizopus oryzae...

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Main Authors: Shirazi, Fazal, Pontikos, Michael A., Walsh, Thomas J., Albert, Nathaniel, Lewis, Russell E., Kontoyiannis, Dimitrios P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754336/
https://ncbi.nlm.nih.gov/pubmed/23817366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00571-13
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