Hyperthermia Sensitizes Rhizopus oryzae to Posaconazole and Itraconazole Action through Apoptosis

The high mortality rate of mucormycosis with currently available monotherapy has created interest in studying novel strategies for antifungal agents. With the exception of amphotericin B (AMB), the triazoles (posaconazole [PCZ] and itraconazole [ICZ]) are fungistatic in vitro against Rhizopus oryzae...

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Autori principali: Shirazi, Fazal, Pontikos, Michael A., Walsh, Thomas J., Albert, Nathaniel, Lewis, Russell E., Kontoyiannis, Dimitrios P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Mechanisms of Action: Physiological Effects
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754336/
https://ncbi.nlm.nih.gov/pubmed/23817366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00571-13
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