GluN2A and GluN2B NMDA Receptor Subunits Differentially Modulate Striatal Output Pathways and Contribute to Levodopa-Induced Abnormal Involuntary Movements in Dyskinetic Rats

[Image: see text] Dual probe microdialysis was used to investigate whether GluN2A and GluN2B NMDA receptor subunits regulate striatal output pathways under dyskinetic conditions. The preferential GluN2A antagonist NVP-AAM077 perfused in the dopamine-depleted striatum of 6-hydroxydopamine hemilesione...

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Main Authors: Mabrouk, Omar S., Mela, Flora, Calcagno, Mariangela, Budri, Mirco, Viaro, Riccardo, Dekundy, Andrzej, Parsons, Christopher G., Auberson, Yves P., Morari, Michele
格式: Artigo
語言:Inglês
出版: American Chemical Society 2013
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656753/
https://ncbi.nlm.nih.gov/pubmed/23611155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400016d
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