NMDA receptor GluN2A/GluN2B subunit ratio as synaptic trait of levodopa-induced dyskinesias: from experimental models to patients

Levodopa-induced dyskinesias (LIDs) are major complications in the pharmacological management of Parkinson’s disease (PD). Abnormal glutamatergic transmission in the striatum is considered a key factor in the development of LIDs. This work aims at: (i) characterizing N-methyl-D-aspartate (NMDA) rece...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Mellone, Manuela, Stanic, Jennifer, Hernandez, Ledia F., Iglesias, Elena, Zianni, Elisa, Longhi, Annalisa, Prigent, Annick, Picconi, Barbara, Calabresi, Paolo, Hirsch, Etienne C., Obeso, Jose A., Di Luca, Monica, Gardoni, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491616/
https://ncbi.nlm.nih.gov/pubmed/26217176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00245
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