Cand1 Promotes Assembly of New SCF Complexes Through Dynamic Exchange of F-box Proteins

The modular SCF ubiquitin ligases feature a large family of substrate receptors that enable recognition of diverse targets. However, how the repertoire of SCF complexes is sustained remains unclear. Real-time measurements of formation and disassembly indicate that SCF(Fbxw7) is extraordinarily stabl...

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Bibliografiske detaljer
Main Authors: Pierce, Nathan W., Lee, J. Eugene, Liu, Xing, Sweredoski, Michael J., Graham, Robert L. J., Larimore, Elizabeth A., Rome, Michael, Zheng, Ning, Clurman, Bruce E., Hess, Sonja, Shan, Shu-ou, Deshaies, Raymond J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656483/
https://ncbi.nlm.nih.gov/pubmed/23453757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.024
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