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Cand1-mediated adaptive exchange mechanism enables variation in F-box protein expression
SCF ubiquitin ligase assembly is regulated by the interplay of substrate binding, reversible Nedd8 conjugation on Cul1, and the F-box protein (FBP) exchange factors Cand1 and Cand2. Detailed investigations into SCF assembly and function in reconstituted systems and Cand1,2 knockout cells informed th...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5836512/ https://ncbi.nlm.nih.gov/pubmed/29499133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.038 |
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