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PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) are the professional interferon (IFN)-producing cells of the immune system. pDCs specifically express Toll-like receptor (TLR)7 and TLR9 molecules and produce massive amounts of type I IFN by sensing microbial nucleic acids via TLR7 and TLR9. Here we report that p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656478/ https://ncbi.nlm.nih.gov/pubmed/22488361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142045 |
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