PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) are the professional interferon (IFN)-producing cells of the immune system. pDCs specifically express Toll-like receptor (TLR)7 and TLR9 molecules and produce massive amounts of type I IFN by sensing microbial nucleic acids via TLR7 and TLR9. Here we report that p...

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Hlavní autoři: Esashi, Eiji, Bao, Musheng, Wang, Yi-Hong, Cao, Wei, Liu, Yong-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656478/
https://ncbi.nlm.nih.gov/pubmed/22488361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142045
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