Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

Plasmacytoid dendritic cells (pDCs) produce copious type I interferon (IFN) upon sensing nucleic acids through Toll-like receptor (TLR) 7 and TLR9. Uncontrolled pDC activation and IFN production are implicated in lymphopenia and autoimmune diseases; therefore, a mechanism controlling pDC IFN product...

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Autori principali: Cao, Wei, Bover, Laura, Cho, Minkwon, Wen, Xiaoxia, Hanabuchi, Shino, Bao, Musheng, Rosen, David B., Wang, Yi-Hong, Shaw, Joanne L., Du, Qiumei, Li, Chun, Arai, Naoko, Yao, Zhengbin, Lanier, Lewis L., Liu, Yong-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715090/
https://ncbi.nlm.nih.gov/pubmed/19564354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090547
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