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Succinate Dehydrogenase Deficiency in Pediatric and Adult Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) in adults are generally driven by somatic gain-of-function mutations in KIT or PDGFRA, and biological therapies targeted to these receptor tyrosine kinases comprise part of the treatment regimen for metastatic and inoperable GISTs. A minority (10–15%) of GISTs...

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Sonraí Bibleagrafaíochta
Main Authors: Belinsky, Martin G., Rink, Lori, von Mehren, Margaret
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656383/
https://ncbi.nlm.nih.gov/pubmed/23730622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00117
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