Adipose-specific Lipoprotein Lipase Deficiency More Profoundly Affects Brown than White Fat Biology

Adipose fat storage is thought to require uptake of circulating triglyceride (TG)-derived fatty acids via lipoprotein lipase (LpL). To determine how LpL affects the biology of adipose tissue, we created adipose-specific LpL knock-out (ATLO) mice, and we compared them with whole body LpL knock-out mi...

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Autors principals: Garcia-Arcos, Itsaso, Hiyama, Yaeko, Drosatos, Konstantinos, Bharadwaj, Kalyani G., Hu, Yunying, Son, Ni Huiping, O'Byrne, Sheila M., Chang, Chuchun L., Deckelbaum, Richard J., Takahashi, Manabu, Westerterp, Marit, Obunike, Joseph C., Jiang, Hongfeng, Yagyu, Hiroaki, Blaner, William S., Goldberg, Ira J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656262/
https://ncbi.nlm.nih.gov/pubmed/23542081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469270
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