Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor.

Three types of mutations were introduced into the platelet-derived growth factor (PDGF) receptor to cause a loss of PDGF-stimulated tyrosine kinase activity: (i) a point mutation of the ATP-binding site, (ii) a deletion of the carboxyl-terminal region, and (iii) replacement of the membrane-spanning...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Escobedo, J A, Barr, P J, Williams, L T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365614/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2854192/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5126-5131.1988
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