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Deletion of the kinase insert sequence of the platelet-derived growth factor beta-receptor affects receptor kinase activity and signal transduction.

A characteristic feature of the platelet-derived growth factor (PDGF) beta-receptor is the presence of an insert sequence in the protein tyrosine kinase domain. A receptor mutant which lacks the entire insert of 98 amino acids was expressed in CHO cells, and its functional characteristics were compa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Severinsson, L, Ek, B, Mellström, K, Claesson-Welsh, L, Heldin, C H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC360881/
https://ncbi.nlm.nih.gov/pubmed/2153924
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