Deletion of the kinase insert sequence of the platelet-derived growth factor beta-receptor affects receptor kinase activity and signal transduction.

A characteristic feature of the platelet-derived growth factor (PDGF) beta-receptor is the presence of an insert sequence in the protein tyrosine kinase domain. A receptor mutant which lacks the entire insert of 98 amino acids was expressed in CHO cells, and its functional characteristics were compa...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Severinsson, L, Ek, B, Mellström, K, Claesson-Welsh, L, Heldin, C H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.2.801-809.1990
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