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CD137 Is Induced by the CD40 Signal on Chronic Lymphocytic Leukemia B Cells and Transduces the Survival Signal via NF-κB Activation

CD137 is a member of the tumor necrosis factor receptor family that is expressed on activated T cells. This molecule provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity....

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Detalhes bibliográficos
Main Authors: Nakaima, Yukana, Watanabe, Ken, Koyama, Takatoshi, Miura, Osamu, Fukuda, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655981/
https://ncbi.nlm.nih.gov/pubmed/23696891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064425
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