CD137 Expression Is Induced by Epstein-Barr Virus Infection through LMP1 in T or NK Cells and Mediates Survival Promoting Signals

To clarify the mechanism for development of Epstein-Barr virus (EBV)-positive T- or NK-cell neoplasms, we focused on the costimulatory receptor CD137. We detected high expression of CD137 gene and its protein on EBV-positive T- or NK-cell lines as compared with EBV-negative cell lines. EBV-positive...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yoshimori, Mayumi, Imadome, Ken-Ichi, Komatsu, Honami, Wang, Ludan, Saitoh, Yasunori, Yamaoka, Shoji, Fukuda, Tetsuya, Kurata, Morito, Koyama, Takatoshi, Shimizu, Norio, Fujiwara, Shigeyoshi, Miura, Osamu, Arai, Ayako
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237363/
https://ncbi.nlm.nih.gov/pubmed/25409517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112564
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