EARLY INTERFERENCE WITH P44/42 MAPK SIGNALING IN HYPOTHALAMIC PARAVENTRICULAR NUCLEUS ATTENUATES ANGIOTENSIN II - INDUCED HYPERTENSION

Blood-borne angiotensin II (ANG II) can upregulate p44/42 mitogen-activated protein kinase (MAPK) signaling and ANG II type-1 receptors (AT(1)R) in the hypothalamic paraventricular nucleus (PVN), a critical cardiovascular and autonomic center. We tested the hypothesis that brain p44/42 MAPK signalin...

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Bibliografiske detaljer
Main Authors: Yu, Yang, Xue, Bao-Jian, Zhang, Zhi-Hua, Wei, Shun-Guang, Beltz, Terry G, Guo, Fang, Johnson, Alan Kim, Felder, Robert B
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655907/
https://ncbi.nlm.nih.gov/pubmed/23438934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00080
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