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Spontaneous inter-conversion of insulin fibril chirality()
Amyloid fibrils are associated with many neurodegenerative diseases and are considered to be the energetically most favorable form of proteins. Here we report that a small pH change initiates spontaneous transformation of insulin fibrils from one polymorph to another. As a result, fibril supramolecu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655902/ https://ncbi.nlm.nih.gov/pubmed/22241279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc16895b |
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