Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF

Intraventricular ependymal infection by adenoviruses expressing brain-derived neurotrophic factor (BDNF) and noggin is sufficient to induce the heterotopic recruitment of new medium spiny neurons to the adult neostriatum, from endogenous subependymal neural progenitor cells. This approach was found...

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Hauptverfasser: Benraiss, A, Bruel-Jungerman, E, Lu, G, Economides, AN, Davidson, B, Goldman, SA
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655807/
https://ncbi.nlm.nih.gov/pubmed/21918547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.114
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