Strong Cortical and Spinal Cord Transduction After AAV7 and AAV9 Delivery into the Cerebrospinal Fluid of Nonhuman Primates

The present study builds on previous work showing that infusion of adeno-associated virus type 9 (AAV9) into the cisterna magna (CM) of nonhuman primates resulted in widespread transduction throughout cortex and spinal cord. Transduction efficiency was severely limited, however, by the presence of c...

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Main Authors: Samaranch, Lluis, Salegio, Ernesto A., San Sebastian, Waldy, Kells, Adrian P., Bringas, John R., Forsayeth, John, Bankiewicz, Krystof S.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655626/
https://ncbi.nlm.nih.gov/pubmed/23517473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.005
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