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β-Tubulin mutations that cause severe neuropathies disrupt axonal transport

Microtubules are fundamental to neuronal morphogenesis and function. Mutations in tubulin, the major constituent of microtubules, result in neuronal diseases. Here, we have analysed β-tubulin mutations that cause neuronal diseases and we have identified mutations that strongly inhibit axonal transpo...

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Detalhes bibliográficos
Main Authors: Niwa, Shinsuke, Takahashi, Hironori, Hirokawa, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655465/
https://ncbi.nlm.nih.gov/pubmed/23503589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.59
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