Kinesin Mutations Cause Motor Neuron Disease Phenotypes by Disrupting Fast Axonal Transport in Drosophila

Previous work has shown that mutation of the gene that encodes the microtubule motor subunit kinesin heavy chain (Khc) in Drosophila inhibits neuronal sodium channel activity, action potentials and neurotransmitter secretion. These physiological defects cause progressive distal paralysis in larvae....

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Bibliographic Details
Main Authors: Hurd, D. D., Saxton, W. M.
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1207603/
https://ncbi.nlm.nih.gov/pubmed/8913751
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