Depletion of Regulatory T Cells in a Mouse Experimental Glioma Model through Anti-CD25 Treatment Results in the Infiltration of Non-Immunosuppressive Myeloid Cells in the Brain

The recruitment and activation of regulatory T cells (Tregs) in the micro-environment of malignant brain tumors has detrimental effects on antitumoral immune responses. Hence, local elimination of Tregs within the tumor micro-environment represents a highly valuable tool from both a fundamental and...

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Main Authors: Maes, Wim, Verschuere, Tina, Van Hoylandt, Anaïs, Boon, Louis, Van Gool, Stefaan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655451/
https://ncbi.nlm.nih.gov/pubmed/23710206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/952469
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