DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma

We studied the feasibility, efficacy, and mechanisms of dendritic cell (DC) immunotherapy against murine malignant glioma in the experimental GL261 intracranial (IC) tumor model. When administered prophylactically, mature DCs (DCm) ex vivo loaded with GL261 RNA (DCm-GL261-RNA) protected half of the...

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Detalhes bibliográficos
Main Authors: Maes, Wim, Rosas, Georgina Galicia, Verbinnen, Bert, Boon, Louis, De Vleeschouwer, Steven, Ceuppens, Jan L., Van Gool, Stefaan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2009
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765342/
https://ncbi.nlm.nih.gov/pubmed/19336528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-004
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