Liver-Derived Systemic Factors Drive b Cell Hyperplasia in Insulin-Resistant States

Integrative organ crosstalk regulates key aspects of energy homeostasis, and its dysregulation may underlie metabolic disorders such as obesity and diabetes. To test the hypothesis that crosstalk between the liver and pancreatic islets modulates β cell growth in response to insulin resistance, we us...

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Bibliographic Details
Main Authors: El Ouaamari, Abdelfattah, Kawamori, Dan, Dirice, Ercument, Liew, Chong Wee, Shadrach, Jennifer L., Hu, Jiang, Katsuta, Hitoshi, Hollister-Lock, Jennifer, Qian, Wei-Jun, Wagers, Amy J., Kulkarni, Rohit N.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655439/
https://ncbi.nlm.nih.gov/pubmed/23375376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.007
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