Liver-Derived Systemic Factors Drive b Cell Hyperplasia in Insulin-Resistant States

Integrative organ crosstalk regulates key aspects of energy homeostasis, and its dysregulation may underlie metabolic disorders such as obesity and diabetes. To test the hypothesis that crosstalk between the liver and pancreatic islets modulates β cell growth in response to insulin resistance, we us...

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Hlavní autoři: El Ouaamari, Abdelfattah, Kawamori, Dan, Dirice, Ercument, Liew, Chong Wee, Shadrach, Jennifer L., Hu, Jiang, Katsuta, Hitoshi, Hollister-Lock, Jennifer, Qian, Wei-Jun, Wagers, Amy J., Kulkarni, Rohit N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655439/
https://ncbi.nlm.nih.gov/pubmed/23375376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.007
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