A Novel Quantitative Fluorescent Reporter Assay for RAG Targets and RAG Activity

Recombination-Activating Genes (RAG) 1 and 2 form the site specific recombinase that mediates V(D)J recombination, a process of DNA editing required for lymphocyte development and responsible for their diverse repertoire of antigen receptors. Mistargeted RAG activity associates with genome alteratio...

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Detalhes bibliográficos
Main Authors: Trancoso, Inês, Bonnet, Marie, Gardner, Rui, Carneiro, Jorge, Barreto, Vasco M., Demengeot, Jocelyne, Sarmento, Leonor M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655321/
https://ncbi.nlm.nih.gov/pubmed/23720659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00110
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