Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae

BACKGROUND: Fungal polyketides include commercially important pharmaceuticals and food additives, e.g. the cholesterol-lowering statins and the red and orange monascus pigments. Presently, production relies on isolation of the compounds from the natural producers, and systems for heterologous produc...

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Hlavní autoři: Rugbjerg, Peter, Naesby, Michael, Mortensen, Uffe H, Frandsen, Rasmus JN
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654996/
https://ncbi.nlm.nih.gov/pubmed/23557488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-12-31
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