Selective removal of alpha heavy-chain glycosylation sites causes immunoglobulin A degradation and reduced secretion.
The importance of carbohydrate in the secretion of immunoglobulin A (IgA) has previously been suggested by results of studies with tunicamycin, which prevents N-linked glycosylation of all cell glycoproteins. To directly evaluate the role of individual oligosaccharides in the secretion of IgA, we ha...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.10.4197-4203.1988 |
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