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Selective removal of alpha heavy-chain glycosylation sites causes immunoglobulin A degradation and reduced secretion.

The importance of carbohydrate in the secretion of immunoglobulin A (IgA) has previously been suggested by results of studies with tunicamycin, which prevents N-linked glycosylation of all cell glycoproteins. To directly evaluate the role of individual oligosaccharides in the secretion of IgA, we ha...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Taylor, A K, Wall, R
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.10.4197-4203.1988
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