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Immunomodulation of the tumor microenvironment by Toll-like receptor-3 (TLR3) ligands

In hepatocellular carcinoma (HCC) patients, the intratumoral expression of Toll-like receptor-3 (TLR3) correlates with prolonged survival. We demonstrated that TLR3 ligands can operate through three independent mechanisms: by directly killing TLR3-expressing cancer cells, by inducing T- and natural...

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Autori principali: Chew, Valerie, Abastado, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654580/
https://ncbi.nlm.nih.gov/pubmed/23734310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23493
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