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Ameliorating the tumor microenvironment for antitumor responses through TLR5 ligand-secreting T cells
Toll-like receptor (TLR) agonists are potent immunostimulatory agents that have demonstrated great potential for cancer immunotherapy. We have genetically-engineered tumor-specific T cells to deliver and secrete the TLR5 ligand (TLR5L) flagellin to the tumor site to provide costimulation for antitum...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839377/ https://ncbi.nlm.nih.gov/pubmed/27141375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1076609 |
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