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High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos
Recently, gene editing with transcription activator-like effector nucleases (TALENs) has been used in the life sciences. TALENs can be easily customized to recognize a specific DNA sequence and efficiently introduce double-strand breaks at the targeted genomic locus. Subsequent non-homologous end-jo...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654262/ https://ncbi.nlm.nih.gov/pubmed/23789092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20133855 |
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