High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos

Recently, gene editing with transcription activator-like effector nucleases (TALENs) has been used in the life sciences. TALENs can be easily customized to recognize a specific DNA sequence and efficiently introduce double-strand breaks at the targeted genomic locus. Subsequent non-homologous end-jo...

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Main Authors: Suzuki, Ken-ichi T., Isoyama, Yukiko, Kashiwagi, Keiko, Sakuma, Tetsushi, Ochiai, Hiroshi, Sakamoto, Naoaki, Furuno, Nobuaki, Kashiwagi, Akihiko, Yamamoto, Takashi
格式: Artigo
語言:Inglês
出版: The Company of Biologists 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654262/
https://ncbi.nlm.nih.gov/pubmed/23789092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20133855
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