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Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes

A prior linkage scan in Pima Indians identified a putative locus for type two diabetes (T2D) and body mass index (BMI) on chromosome 11q23-25. Association mapping across this region identified single nucleotide polymorphisms (SNPs) in the trehalase gene (TREH) that were associated with T2D. To asses...

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Detalhes bibliográficos
Main Authors: Muller, Yunhua L., Hanson, Robert L., Knowler, William C., Fleming, Jamie, Goswami, Jayita, Huang, Ke, Traurig, Michael, Sutherland, Jeff, Wiedrich, Chris, Wiedrich, Kim, Mahkee, Darin, Ossowski, Vicky, Kobes, Sayuko, Bogardus, Clifton, Baier, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654185/
https://ncbi.nlm.nih.gov/pubmed/23468175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1278-3
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