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Alternative CHRNB4 3′-UTRs Mediate the Allelic Effects of SNP rs1948 on Gene Expression

Common genetic factors strongly contribute to both nicotine, the main addictive component of tobacco, and alcohol use. Several lines of evidence suggest nicotinic acetylcholine receptors as common sites of action for nicotine and alcohol. Specifically, rs1948, a single-nucleotide polymorphism (SNP)...

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Detalles Bibliográficos
Main Authors: Gallego, Xavier, Cox, Ryan J., Laughlin, James R., Stitzel, Jerry A., Ehringer, Marissa A
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653846/
https://ncbi.nlm.nih.gov/pubmed/23691088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063699
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