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Alternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expression.

Common genetic factors strongly contribute to both nicotine, the main addictive component of tobacco, and alcohol use. Several lines of evidence suggest nicotinic acetylcholine receptors as common sites of action for nicotine and alcohol. Specifically, rs1948, a single-nucleotide polymorphism (SNP)...

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Detalhes bibliográficos
Main Authors: Xavier Gallego, Ryan J Cox, James R Laughlin, Jerry A Stitzel, Marissa A Ehringer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3653846?pdf=render
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