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Nicotinic acetylcholine receptors: upregulation, age-related effects, and associations with drug use

Nicotinic acetylcholine receptors are ligand-gated ion channels that exogenously bind nicotine. Nicotine produces rewarding effects by interacting with these receptors in the brain’s reward system. Unlike other receptors, chronic stimulation by an agonist induces an upregulation of receptor number t...

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Detalhes bibliográficos
Publicado no:Genes Brain Behav
Main Authors: Melroy-Greif, Whitney E., Stitzel, Jerry A., Ehringer, Marissa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780670/
https://ncbi.nlm.nih.gov/pubmed/26351737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12251
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