Cellular DNA rearrangements and early developmental arrest caused by DNA insertion in transgenic mouse embryos.
Insertional mutagenesis was investigated in a transgenic mouse strain (HUGH/4) derived from a fertilized egg injected with plasmid DNA containing the human growth hormone gene. Lethality occurred in homozygous embryos and was traced to the egg cylinder stage on days 4 to 5 of gestation, shortly afte...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1987
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365348/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.6.2243-2247.1987 |
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