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Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions
Activation-induced deaminase (AID) initiates diversity of immunoglobulin genes through deamination of cytosine to uracil. Two opposing models have been proposed for the deamination of DNA or RNA by AID. Although most data support DNA deamination, there is no physical evidence of uracil residues in i...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653439/ https://ncbi.nlm.nih.gov/pubmed/21151102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1970 |
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