Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions

Activation-induced deaminase (AID) initiates diversity of immunoglobulin genes through deamination of cytosine to uracil. Two opposing models have been proposed for the deamination of DNA or RNA by AID. Although most data support DNA deamination, there is no physical evidence of uracil residues in i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Maul, Robert W, Saribasak, Huseyin, Martomo, Stella A, McClure, Rhonda L, Yang, William, Vaisman, Alexandra, Gramlich, Hillary S, Schatz, David G, Woodgate, Roger, Wilson, David M, Gearhart, Patricia J
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653439/
https://ncbi.nlm.nih.gov/pubmed/21151102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1970
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker