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Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor
Linkage-specific ubiquitination often leads to distinct cellular events. It has been difficult to establish definitively the requirement for a particular linkage in mammalian degradation pathways due to the inability to deplete endogenous ubiquitin while maintaining cell viability. The E3 ubiquitin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653405/ https://ncbi.nlm.nih.gov/pubmed/23419260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035774 |
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