Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

Eitemau Tebyg

• Control of Cholesterol Synthesis through Regulated ER-Associated Degradation of HMG CoA Reductase
  gan: Jo, Youngah, et al.
  Cyhoeddwyd: (2010)
• Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8
  gan: Jo, Youngah, et al.
  Cyhoeddwyd: (2011)
• The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
  gan: Schumacher, Marc M, et al.
  Cyhoeddwyd: (2015)
• Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver
  gan: Hwang, Seonghwan, et al.
  Cyhoeddwyd: (2017)
• Feedback Regulation of Cholesterol Synthesis: Sterol-Accelerated Ubiquitination and Degradation of HMG CoA Reductase
  gan: DeBose-Boyd, Russell A.
  Cyhoeddwyd: (2008)