Carregant...

Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

In mammalian cells, levels of the integral membrane proteins 3-hydroxy-3-methylglutaryl-CoA reductase and Insig-1 are controlled by lipid-regulated endoplasmic reticulum-associated degradation (ERAD). The ERAD of reductase slows a rate-limiting step in cholesterol synthesis and results from sterol-i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Faulkner, Rebecca A., Nguyen, Andrew D., Jo, Youngah, DeBose-Boyd, Russell A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653402/
https://ncbi.nlm.nih.gov/pubmed/23403031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033639
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!