IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in chronic hepatitis C patients

Genetic variation in the IL28B region has been associated with sustained virological response (SVR) rates in chronic hepatitis C (CHC) patients treated with peginterferon-α and ribavirin. We hypothesized that IL28B polymorphism is associated with intrahepatic expression of interferon-stimulated gene...

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Detalhes bibliográficos
Main Authors: Urban, Thomas J., Thompson, Alexander J., Bradrick, Shelton, Fellay, Jacques, Schuppan, Detlef, Cronin, Kenneth D., Hong, Linda, McKenzie, Alexander, Patel, Keyur, Shianna, Kevin V., McHutchison, John G., Goldstein, David B., Afdhal, Nezam
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653303/
https://ncbi.nlm.nih.gov/pubmed/20931559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23912
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