IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in chronic hepatitis C patients

Genetic variation in the IL28B region has been associated with sustained virological response (SVR) rates in chronic hepatitis C (CHC) patients treated with peginterferon-α and ribavirin. We hypothesized that IL28B polymorphism is associated with intrahepatic expression of interferon-stimulated gene...

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Autores principales: Urban, Thomas J., Thompson, Alexander J., Bradrick, Shelton, Fellay, Jacques, Schuppan, Detlef, Cronin, Kenneth D., Hong, Linda, McKenzie, Alexander, Patel, Keyur, Shianna, Kevin V., McHutchison, John G., Goldstein, David B., Afdhal, Nezam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653303/
https://ncbi.nlm.nih.gov/pubmed/20931559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23912
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