Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-α Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia

Acute stress reduces pain sensitivity by engaging an endocannabinoid signaling circuit in the midbrain. The neural mechanisms governing this process and molecular identity of the endocannabinoid substance(s) involved are unknown. We combined behavior, pharmacology, immunohistochemistry, RNA interfer...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gregg, Laura C., Jung, Kwang-Mook, Spradley, Jessica M., Nyilas, Rita, Suplita, Richard L., Zimmer, Andreas, Watanabe, Masahiko, Mackie, Ken, Katona, István, Piomelli, Daniele, Hohmann, Andrea G.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2012
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652685/
https://ncbi.nlm.nih.gov/pubmed/22787031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0013-12.2012
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires