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Structure of PolIIIα-τ(c)-DNA complex suggests an atomic model of the replisome

The C-terminal domain (CTD) of τ subunit of the clamp loader (τ(c)) binds to both the DnaB helicase and the DNA polymerase III α subunit (PolIIIα), and determines their relative positions and orientations on the leading and lagging strands. Here we present a 3.2 Å resolution structure of Thermus aqu...

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Bibliografiske detaljer
Main Authors: Liu, Bin, Lin, Jinzhong, Steitz, Thomas A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652607/
https://ncbi.nlm.nih.gov/pubmed/23478062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.02.002
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