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Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-subunit

The crystal structure of the catalytic subunit of the DNA Polymerase III holoenzyme (PolIIIα) bound to primer-template DNA and an incoming deoxynucleoside triphosphate has been determined at 4.6 Å resolution. The polymerase interacts with the sugar phosphate backbone of the DNA across its minor groo...

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Detalhes bibliográficos
Main Authors: Wing, Richard A., Bailey, Scott, Steitz, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614274/
https://ncbi.nlm.nih.gov/pubmed/18691598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.07.058
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