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Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing

The competition between viruses and hosts is played out in all branches of life. Many prokaryotes have an adaptive immune system termed ‘CRISPR’ (clustered regularly interspaced short palindromic repeats) which is based on the capture of short pieces of viral DNA. The captured DNA is integrated into...

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Detalhes bibliográficos
Main Authors: Reeks, Judith, Sokolowski, Richard D., Graham, Shirley, Liu, Huanting, Naismith, James H., White, Malcolm F.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652601/
https://ncbi.nlm.nih.gov/pubmed/23527601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130269
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